Study on Itching in Allergic Drug Eruption

Allergic drug eruption secondary to intravenous acyclovir.

A 62-year-old woman presented at our department 10 days after returning from a trip to Alaska. Over the previous 7 days she had developed headache, elevated temperature and disseminated erythematous vesicles. The only medication she was taking at this time was L-thyroxine 75 mg once daily for treatment of hypothyroidism. Her skin showed widespread vesicles on an erythematous base without palmar...

Fixed drug eruption: A descriptive study of 100 cases

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Pathophysiology of itching and sneezing in allergic rhinitis.

Itching and sneezing represent two of the main bothersome symptoms, apart from nasal obstruction and rhinorrhea in allergic rhinitis. Apparently, activation of the central and peripheral nervous system plays a major role in the pathophysiology of this process. Sensory nerves of the afferent trigeminal system including myelinated Adelta-fibres and thin, non-myelinated C-fibres of the nasal mucos...

Fixed drug eruption in male genitalia: A cross-sectional study from Iran

Background: Fixed drug eruption (FDE) is an uncommon adverse reaction to medications. Mucosal areas, particularly the male genitalia, are favored sites. To our knowledge, no study has investigated the causative agent(s) in FDE occurring on male genitals of Iranian patients. So, we conducted a study to determine the most common agents and areas of involvement in fixed genital drug eruption of ma...

Mucosal fixed drug eruption.